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Current oral B12 supplements either rely on passive diffusion, which is often inadequate for IF-deficient patients, or use porcine-derived intrinsic factor, which can trigger immune responses and has not been systematically optimised for therapeutic use
[2] [3] Bruising occurs when small blood vessels (capillaries) beneath the skin are damaged during needle insertion, causing blood to leak into surrounding tissues
That said , the study provides useful reassurance about the safety of this class of drugs
The efficacy of semaglutide in controlling blood glucose levels and facilitating weight loss, along with the cardiovascular benefits demonstrated in the SUSTAIN-6 and PIONEER-6 trials, has expanded its clinical utility, potentially making it a first-line choice for many patients
